One of the most common reasons for staying up later than usual is to go to a party, where alcohol may be drunk. The social use of alcohol depends largely on its ability to remove inhibiting factors in our personalities and conversation, thereby making us perhaps more interesting and amusing. A similar removal of inhibition of an epileptic focus may allow a seizure to occur. Often, however,’ the seizure occurs during the ‘hangover’, at a time when the blood alcohol is falling, or near zero. It is probable that other changes in body chemistry, particularly in the distribution of water within and outside cells, plays a part in causing such seizures. Over-hydration of experimental animals with epilepsy may precipitate seizures, so there are grounds for believing that large quantities of beer, containing both alcohol and much water, may be more likely to precipitate an attack than moderate use of wine or spirits.


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